Scientist, Purification Process Science

Company: Thermo Fisher Scientific
Location: Wilmington
Posted on: February 9, 2025

Job Description:

Work ScheduleStandard (Mon-Fri)Environmental ConditionsOfficeJob DescriptionScientist, Purification Process Science Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission - to enable our customers to make the world healthier, safer, and cleaner. At PPD, part of Thermo Fisher Scientific, we hire the best, develop ourselves and each other, and recognize the power of being one team. It's not just talk; our award-winning training programs speak for themselves. Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to demonstrate the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.Location/Division Specific InformationOnsite in Wilmington, DEOur client is seeking a motivated and dedicated protein purification scientist to support protein purification process development and optimization primarily for novel therapeutic monoclonal antibody products including bispecifics throughout all stages of clinical trials. A day in the life:

• Conduct routine protein purification to support formulation team's material needs and cell culture development
• Conduct high-throughput protein purification to support cell line development
• Provide assistance in purification process development, optimization, and scale-up manufacturing
• Conduct routine analyses of in-process samples using relevant product purity and process impurity analytical tools
• Prepare buffers and solutions needed for laboratory work
• Present work summary in the group meeting
• Write routine electronic laboratory notebook
• Other responsibilities as assignedEducation and Experience
  • BS degree in biochemistry, bioengineering, biology, chemistry or related fields, preferably with some relevant industry experiences with 2-4 years of experience or MS in above fields with 0-2 years of experience. In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role. Knowledge, Skills and Abilities:
    • Good knowledge in protein chemistry and bioprocessing
    • Good knowledge and hands-on experiences in various types of column/membrane chromatography (affinity, size exclusion, ion exchanges, multi-mode) and filtration technology; TFF
    • Experiences in using AKTA line of purification instruments
    • Experiences in using ultrafiltration/diafiltration instrument for buffer exchange, product concentration, and formulation
    • Experiences in protein analysis such as HPLC, CGE, ELISA, etc. is a plus
    • Aseptic Technique
    • Good verbal and written communication skills, organized, cooperative, independent, meticulous
    • Experiences in high-throughput protein purification platform are desirable but not required.Physical Requirements / Work Environment Thermo Fisher Scientific values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:
      • Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
      • Able to work upright and stationary and/or standing for typical working hours.
      • Able to lift and move objects up to 25 pounds.
      • Able to work in non-traditional work environments.
      • Able to use and learn standard office equipment and technology with proficiency.
      • May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
      • Able to perform successfully under pressure while prioritizing and handling multiple projects or activities. BenefitsWe offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us. As one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological

Keywords: Thermo Fisher Scientific, Wilmington , Scientist, Purification Process Science, Other , Wilmington, Delaware